Systemic Lupus Erythematosus (SLE) : Causes,Clinical Picture,Investigations & Treatment

Systemic Lupus Erythematosis

Defination

  • Systemic lupus Erythematosus (SLE) is a multi-framework auto-safe sickness that is caused by tissue harm coming about because of counter acting agent and supplement settling invulnerable complex statement.
  • It is described by conditions of intensification and reduction.
  • The safe framework loses the  ability to separate between outside cells and it’s own particular cells and tissues
  • Antibodies against the safe framework are shaped.
  • The safe edifices that are shaped develop in the tissue causing aggravation, damage to the tissue, and agony.

Occurrence OF Systemic lupus Erythematosus :

Between 500,000 to 1.5 million Americans have lupus.

80-90% of Systemic Lupus Erythematosus patients are female.

80% of Systemic Lupus Erythematosus patients are in the vicinity of 15 and 45 years old.

Lupus influences more African Americans, Asian Americans, Hispanics, and Native Americans than Caucasians.

WHAT CAUSES LUPUS?

  • Hereditary qualities
  • Hormones
  • Condition

Etiology

  • The particular reason is obscure
  • Hereditary elements may play a  role
  • Ecological specialists
  • Medications or other synthetic specialists
  • Dietary elements
  • Bright radiation
  • Irresistible specialists

Types OF LUPUS

  1. Discoid or Cutaneous Lupus (DLE)
  2. Medication Induced Lupus (DIL)
  3. Neonatal Lupus
  4. Systemic Lupus Erythematosus (SLE)

Normal SYMPTOMS OF SLE

Throbbing joints

Fever

Weariness

Skin Rashes

Different LUPUS SYMPTOMS

Chest torment

Male pattern baldness

Mouth wounds

Photosensitivity

Paleness

Rehashed unnatural birth cycles

Cerebral pain

Dazedness

Sorrow

Seizures

Memory aggravations

ORGAN INVOLVEMENT WITH

Systems-Affected-by-Lupus
Systems-Affected-by-Lupus

 

  • Kidneys
  • Lungs
  • Focal nervous system
  • Veins
  • Blood
  • Heart

DIAGNOSING Systemic lupus erythematosus 

Restorative history (counting family history)

Finish physical examination

Research facility tests

Skin or kidney biopsy

ACR DIAGNOSTIC CRITERIA

Skin Rash

    • Butterfly rash
    • Discoid rash
    • Photosensitivity
    •  Oral ulcers

Systemic criteria

  • Joint pain
  • Serositis
  • Kidney issue
  • Neurologic confusion

Research center criteria

  • Immunologic disorder
  • Antinuclear antibody
  • Hematologic abnormalities

Systemic Lupus Erythematosus TREATMENT

  • Tentative
  • Team effort
  • Tailored

Basic LUPUS MEDICATIONS

NSAIDs

Antimalarials

Corticosteroids

Immunosuppressants

Biologicals (Belimumab)

Investigational (look into)

systemic lupus erythematosus (SLE) is the most common form and has the widest array of symptoms.

Comment

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